The Photobiology of Lutein and Zeaxanthin in the Eye.

نویسندگان

  • Joan E Roberts
  • Jessica Dennison
چکیده

Lutein and zeaxanthin are antioxidants found in the human retina and macula. Recent clinical trials have determined that age- and diet-related loss of lutein and zeaxanthin enhances phototoxic damage to the human eye and that supplementation of these carotenoids has a protective effect against photoinduced damage to the lens and the retina. Two of the major mechanisms of protection offered by lutein and zeaxanthin against age-related blue light damage are the quenching of singlet oxygen and other reactive oxygen species and the absorption of blue light. Determining the specific reactive intermediate(s) produced by a particular phototoxic ocular chromophore not only defines the mechanism of toxicity but can also later be used as a tool to prevent damage.

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عنوان ژورنال:
  • Journal of ophthalmology

دوره 2015  شماره 

صفحات  -

تاریخ انتشار 2015